概述

  • 产品名称Anti-Renin抗体
    参阅全部 Renin 一抗
  • 描述
    兔多克隆抗体to Renin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Monkey
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 70 - 302 of Human Renin (NP_000528).

  • 阳性对照
    • 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab97570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 45 kDa.

靶标

  • 功能Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
  • 疾病相关Defects in REN are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
    Defects in REN are the cause of familial juvenile hyperuricemic nephropathy type 2 (HNFJ2) [MIM:613092]. It is a renal disease characterized by juvenile onset of hyperuricemia, slowly progressive renal failure and anemia.
  • 序列相似性Belongs to the peptidase A1 family.
  • 细胞定位Secreted. Membrane. Associated to membranes via binding to ATP6AP2.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Angiotensin forming enzyme antibody
    • Angiotensin forming enzyme precursor antibody
    • Angiotensinogenase antibody
    • Angiotensinogenase precursor antibody
    • FLJ10761 antibody
    • HNFJ2 antibody
    • REN antibody
    • Ren1 antibody
    • RENI_HUMAN antibody
    • Renin antibody
    • Renin precursor renal antibody
    see all

Anti-Renin antibody 图像

  • Anti-Renin antibody (ab97570) at 1/1000 dilution + 293T whole cell lysate at 30 µg

    Predicted band size : 45 kDa

Anti-Renin antibody (ab97570)参考文献

ab97570 has not yet been referenced specifically in any publications.

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