概述

  • 产品名称Anti-Reg3a抗体
    参阅全部 Reg3a 一抗
  • 描述
    兔多克隆抗体to Reg3a
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH selected from the N terminal region of Human Reg3a (NP_002571.1)

  • 阳性对照
    • 293 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab95316 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 19 kDa.

靶标

  • 功能Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
  • 组织特异性Highly expressed in epidermal keratinocytes of psoriasis patients (at protein level). Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
  • 序列相似性Contains 1 C-type lectin domain.
  • 结构域The EPN motif is essential for recognition of the peptidoglycan carbohydrate backbone and for efficient bacterial killing with Glu-114 playing a key role in peptidoglycan binding and bactericidal activity.
  • 翻译后修饰Proteolytic processing by trypsin removes an inhibitory N-terminal propeptide and is essential for peptidoglycan binding and antibacterial activity.
  • 细胞定位Secreted. Found in the apical region of pancreatic acinar cells.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ18565 antibody
    • Hepatocarcinoma intestine pancreas antibody
    • Hepatointestinal pancreatic protein antibody
    • HIP antibody
    • HIP/PAP antibody
    • Human proislet peptide antibody
    • INGAP antibody
    • Pancreatic beta cell growth factor antibody
    • Pancreatitis associated protein 1 antibody
    • Pancreatitis associated protein antibody
    • Pancreatitis-associated protein 1 antibody
    • PAP antibody
    • PAP H antibody
    • PAP homologous protein antibody
    • PAP1 antibody
    • PBCGF antibody
    • Proliferation inducing protein 34 antibody
    • Proliferation inducing protein 42 antibody
    • Reg III alpha antibody
    • REG III antibody
    • Reg III-alpha antibody
    • REG-3-alpha antibody
    • REG3 antibody
    • Reg3a antibody
    • REG3A_HUMAN antibody
    • Regenerating islet derived 3 alpha antibody
    • Regenerating islet derived protein 3 alpha precursor antibody
    • Regenerating islet-derived protein 3-alpha 15 kDa form antibody
    • Regenerating islet-derived protein III-alpha antibody
    see all

Anti-Reg3a antibody 图像

  • Anti-Reg3a antibody (ab95316) at 1/100 dilution (in TTBS/1% NFDM for 1 hr. at room temperature) + 293 cell line lysate at 35 µg

    Secondary
    Enzyme-linked secondary antibody (typically horseradish peroxidase or alkaline phosphatase) in TTBS/1% NFDM for 30 min. at room temperature.

    Predicted band size : 19 kDa

Anti-Reg3a antibody (ab95316)参考文献

ab95316 has not yet been referenced specifically in any publications.

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