概述

  • 产品名称Anti-REEP1抗体
  • 描述
    兔多克隆抗体to REEP1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 110-159 (AKDRSYDALV HFGKRGLNVA ATAAVMAASK GQGALSERLR SFSMQDLTTI) of Human REEP1 (NP_075063).

  • 阳性对照
    • Human fetal brain lysate.

性能

应用

Our Abpromise guarantee covers the use of ab105583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May enhance the cell surface expression of odorant receptors.
  • 疾病相关Defects in REEP1 are the cause of spastic paraplegia autosomal dominant type 31 (SPG31) [MIM:610250]. Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body.
  • 序列相似性Belongs to the DP1 family.
  • 细胞定位Mitochondrion membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C2orf23 antibody
    • Chromosome 2 open reading frame 23 antibody
    • FLJ13110 antibody
    • Receptor accessory protein 1 antibody
    • Receptor expression-enhancing protein 1 antibody
    • Reep1 antibody
    • REEP1_HUMAN antibody
    • SPG31 antibody
    see all

Anti-REEP1 antibody 图像

  • Anti-REEP1 antibody (ab105583) at 1 µg/ml + Human fetal brain lysate at 10 µg

    Predicted band size : 22 kDa

Anti-REEP1 antibody (ab105583)参考文献

ab105583 has not yet been referenced specifically in any publications.

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