Recombinant Staphylokinase protein (ab73828)

概述

  • 产品名称Recombinant Staphylokinase protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 序列The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ser-Ser-Phe-Asp.

技术指标

Our Abpromise guarantee covers the use of ab73828 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The biological activity is measured by the ability of fibrin lysis in agarose plate was found to be 4600 IU/mg.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purified by proprietary chromatographic techniques. Purity: Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20mM PBS, pH 7

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶 Reconstitute the lyophilized product in sterile 18MOhm-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

常规信息

  • 别名
    • Neutral proteinase
    • Protease III
    • SAK
    • SakSTAR
  • 相关性Staphylokinase (SAK) is a 136-amino acid enzyme from Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen to form plasmin, which digest fibrin clots. This disrupts the fibrin meshwork which can often form to keep an infection localized. Staphylokinase also cleaves IgG and complement component C3b, inhibiting phagocytosis.
  • 细胞定位Secreted

Recombinant Staphylokinase protein (ab73828)参考文献

ab73828 has not yet been referenced specifically in any publications.

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