Recombinant Staphylococcus aureus protein (ab68923)

概述

  • 产品名称Recombinant Staphylococcus aureus protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli

技术指标

Our Abpromise guarantee covers the use of ab68923 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Activity: Greater than 95% binding activity to human IgG.
  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    Staphylococal Protein A was purified by proprietary chromatographic techniques. Purity: Greater than 90.0% as determined by: (a) Analysis by RP-HPLC. (b) Anion-exchange FPLC. (c) Analysis by reducing and non-reducing SDS-PAGE, Silver Stained. Note: A specific purification process was used to get the recombinant protein A with the purity of more than 98% , no human IgG affinity step is used during validated fermentation and purification and the protein is devoid of bacterial contaminants found normally in native Protein A. (Free of Staphylococcus endotoxins and hemolysin).
  • 形式Liquid
  • 补充说明


    This protein was produced by expressing a modified protein A gene in E.coli.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 1X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • IgG binding protein A
    • Immunoglobulin G binding protein A
    • SPA
  • 相关性S.aureus binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface, which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.
  • 细胞定位Secreted; cell wall.

Recombinant Staphylococcus aureus protein (ab68923)参考文献

ab68923 has not yet been referenced specifically in any publications.

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