This product is an active protein and may elicit a biological response in vivo, handle with caution.
C type lectin domain family 11 member A
C type lectin superfamily member 3
C-type lectin domain family 11 member A
C-type lectin superfamily member 3
Lymphocyte secreted C type lectin
Lymphocyte secreted C-type lectin
Stem cell growth factor
功能Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
组织特异性Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
序列相似性Contains 1 C-type lectin domain.
发展阶段In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.
翻译后修饰O-glycosylated. Probably sulfated on the O-glycans.