Recombinant SCGF beta protein (ab9836)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli

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技术指标

Our Abpromise guarantee covers the use of ab9836 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 形式Lyophilised
  • 补充说明The ED50, determined by its inhibitory effect on the proliferation of TF-1 cells previously grown in media containing GM-CSF, is <7.0ng/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 7
    Constituents: 0.16% Sodium phosphate, 0.18% Sodium chloride, 0.015% DTT

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • C type lectin domain family 11 member A
    • C type lectin superfamily member 3
    • C-type lectin domain family 11 member A
    • C-type lectin superfamily member 3
    • CLC11_HUMAN
    • CLEC11A
    • CLECSF3
    • LSLCL
    • Lymphocyte secreted C type lectin
    • Lymphocyte secreted C-type lectin
    • p47
    • Stem cell growth factor
    see all
  • 功能Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.
  • 组织特异性Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.
  • 序列相似性Contains 1 C-type lectin domain.
  • 发展阶段In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.
  • 翻译后修饰O-glycosylated. Probably sulfated on the O-glycans.
  • 细胞定位Cytoplasm. Secreted.
  • Information by UniProt

Recombinant SCGF beta protein (ab9836)参考文献

ab9836 has not yet been referenced specifically in any publications.

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