Recombinant S. cerevisiae Isocitrate dehydrogenase protein (ab73438)

概述

描述

  • 性质Recombinant
  • 来源Saccharomyces cerevisiae
  • 氨基酸序列
    • 种属Saccharomyces cerevisiae

技术指标

Our Abpromise guarantee covers the use of ab73438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity was found to be 30 IU/mg.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab73438 was purified by proprietary chromatographic techniques. Purity is greater than 95.0% as determined by RP-HPLC and SDS-PAGE.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 50% Glycerol, Potassium phosphate, pH 7.1

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Cytosolic NADP isocitrate dehydrogenase
    • Cytosolic NADP-isocitrate dehydrogenase
    • Epididymis luminal protein 216
    • Epididymis secretory protein Li 26
    • HEL-216
    • HEL-S-26
    • ICDH
    • IDCD
    • IDH
    • IDH1
    • IDHC_HUMAN
    • IDP
    • IDPC
    • Isocitrate dehydrogenase [NADP] cytoplasmic
    • Isocitrate dehydrogenase 1 (NADP+) soluble
    • NADP dependent isocitrate dehydrogenase cytosolic
    • NADP dependent isocitrate dehydrogenase peroxisomal
    • NADP(+)-specific ICDH
    • Oxalosuccinate decarboxylase
    • PICD
    see all
  • 疾病相关Glioma
    Genetic variations are associated with cartilaginous tumors such as enchondroma or chondrosarcoma. Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha-ketoglutarate is converted to R(-)-2-hydroxyglutarate.
  • 序列相似性Belongs to the isocitrate and isopropylmalate dehydrogenases family.
  • 翻译后修饰Acetylation at Lys-374 dramatically reduces catalytic activity.
  • 细胞定位Cytoplasm. Peroxisome.
  • Information by UniProt

Recombinant S. cerevisiae Isocitrate dehydrogenase protein (ab73438)参考文献

ab73438 has not yet been referenced specifically in any publications.

Product Wall

Gene used in the over-expression system originates from Saccharomyces Cerevisiae.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"