Recombinant Rubella virus E1 protein (ab107947)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列

技术指标

Our Abpromise guarantee covers the use of ab107947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

  • 纯度> 80 % SDS-PAGE.
    ab107947 is purified by Metal affinity chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: 0.1% Sodium Azide
    Constituents: 1mM Hydrochloric acid

常规信息

  • 别名
    • E1
    • E1 envelope glycoprotein
    • Glycoprotein E1
    • Spike glycoprotein E1
  • 相关性Rubella virus is the only member of the Rubrivirus genus of the Togavirus family. Unlike most Togaviruses it is NOT arthropod borne, but is acquired via the respiratory route. It is an enveloped (toga=cloak), non-segmented, positive sense, RNA virus and replicates in the cytoplasm. It consists of 3 structural proteins; E1,E2 membrane bound glycoproteins, and C capsid protein. E1 envelope glycoprotein is a class II viral fusion protein. Fusion activity is inactive as long as E1 is bound to E2 in mature virion. After virus attachment to target cell and endocytosis, acidification of the endosome induces dissociation of E1/E2 heterodimer and trimerization of the E1 subunits. This E1 homotrimer is fusion active, and promotes release of viral nucleocapsid in the cytoplasm after cell and viral membrane fusion. The E1 cytoplasmic tail modulates virus release, and the tyrosines residues are critical for this function.

Recombinant Rubella virus E1 protein (ab107947)参考文献

ab107947 has not yet been referenced specifically in any publications.

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