重组恒河猴IL-13蛋白(Active) (ab216214)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, SDS-PAGE, Functional Studies
描述
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产品名称
重组恒河猴IL-13蛋白(Active)
参阅全部 IL-13 蛋白酶 -
生物活性
ab216214 is fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using Human TF-1 cells is less than 5 ng/ml, corresponding to a specific activity of > 2.0 × 105 IU/mg.
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纯度
> 98 % SDS-PAGE.
>98 % by HPLC.. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Rhesus monkey -
序列
SPSPVPRSTA LKELIEELVN ITQNQKAPLC NGSMVWSINL TAGVYCAALE SLINVSGCSA IEKTQRMLNG FCPHKVSAGQ FSSLRVRDTK IEVAQFVKDL LVHLKKLFRE GRFN -
预测分子量
13 kDa -
氨基酸
19 to 132 -
额外的序列信息
A single non-glycosylated polypeptide chain containing 114 amino acids. This product is for the mature full length protein. The signal peptide is not included.
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技术指标
Our Abpromise guarantee covers the use of ab216214 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
HPLC
SDS-PAGE
Functional Studies
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituents: 97% PBS, 3% Trehalose
Lyophilized from a 0.2 µm filtered concentrated solution.This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Briefly centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
常规信息
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别名
- Allergic rhinitis
- ALRH
- BHR 1
see all -
功能
Cytokine (PubMed:8096327, PubMed:8097324). Inhibits inflammatory cytokine production (PubMed:8096327). Synergizes with IL2 in regulating interferon-gamma synthesis (PubMed:8096327). May be critical in regulating inflammatory and immune responses (PubMed:8096327, PubMed:8097324). Positively regulates IL31RA expression in macrophages. -
疾病相关
Allergic rhinitis -
序列相似性
Belongs to the IL-4/IL-13 family. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab216214 尚未被引用在任何文献中。