重组大鼠RBP4蛋白(ab109146)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Endotoxin level: < 0.100 Eu/µg
- Tags: DDDDK tag N-Terminus
- Suitable for: SDS-PAGE
描述
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产品名称
重组大鼠RBP4蛋白
参阅全部 RBP4 蛋白酶 -
纯度
> 90 % SDS-PAGE.
ab109146 is 0.2µm filtered -
内毒素水平
< 0.100 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Rat -
预测分子量
23 kDa including tags -
氨基酸
19 to 201 -
标签
DDDDK tag N-Terminus
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相关产品
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Related Products
技术指标
Our Abpromise guarantee covers the use of ab109146 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Liquid -
补充说明
Working aliquots are stable for up to 3 months when stored at -20°C. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
pH: 7.20
Constituent: PBS
常规信息
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别名
- OTTHUMP00000020114
- OTTHUMP00000020115
- OTTHUMP00000020116
see all -
功能
Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli. -
疾病相关
Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium. -
序列相似性
Belongs to the calycin superfamily. Lipocalin family. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (2)
ab109146 被引用在 2 文献中.
- Zhou W et al. The Effects of RBP4 and Vitamin D on the Proliferation and Migration of Vascular Smooth Muscle Cells via the JAK2/STAT3 Signaling Pathway. Oxid Med Cell Longev 2022:3046777 (2022). PubMed: 35082965
- Zhou W et al. Elevated retinol binding protein 4 levels are associated with atherosclerosis in diabetic rats via JAK2/STAT3 signaling pathway. World J Diabetes 12:466-479 (2021). PubMed: 33889291