Recombinant大鼠Prorenin protein (ab92748)

概述

描述

  • 性质Recombinant
  • 来源HEK 293 cells
  • 氨基酸序列
    • 种属Rat

技术指标

Our Abpromise guarantee covers the use of ab92748 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purified by chelated metal affinity chromatography
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Tris, pH 8.0

常规信息

  • 别名
    • Angiotensin forming enzyme
    • Angiotensinogenase
    • FLJ10761
    • HNFJ2
    • REN
    • Ren1
    • RENAA
    • RENI_HUMAN
    • Renin
    • Renin precursor renal
    • Renin-1
    • Renin-2
    see all
  • 功能Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
  • 疾病相关Defects in REN are a cause of renal tubular dysgenesis (RTD) [MIM:267430]. RTD is an autosomal recessive severe disorder of renal tubular development characterized by persistent fetal anuria and perinatal death, probably due to pulmonary hypoplasia from early-onset oligohydramnios (the Potter phenotype).
    Defects in REN are the cause of familial juvenile hyperuricemic nephropathy type 2 (HNFJ2) [MIM:613092]. It is a renal disease characterized by juvenile onset of hyperuricemia, slowly progressive renal failure and anemia.
  • 序列相似性Belongs to the peptidase A1 family.
  • 细胞定位Secreted. Membrane. Associated to membranes via binding to ATP6AP2.
  • Information by UniProt

Recombinant Rat Prorenin protein 图像

  • 10% SDS PAGE analysis of ab92748.
    Lane 1. 3ug ab92748 non reduced.
    Lane 2. 3ug ab92748 reduced.
    Lane 3. Prestained standard.

Recombinant Rat Prorenin protein (ab92748)参考文献

ab92748 has not yet been referenced specifically in any publications.

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