Recombinant大鼠Progerin protein (ab93917)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Rat

技术指标

Our Abpromise guarantee covers the use of ab93917 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol

常规信息

  • 别名
    • 70 kDa lamin
    • CDCD1
    • CDDC
    • CMD1A
    • CMT2B1
    • EMD2
    • FPL
    • FPLD
    • HGPS
    • IDC
    • LA delta 50
    • Lamin A delta 50
    • LDP1
    • LFP
    • LGMD1B
    • LMN1
    • LMNA
    • LMNC
    • PRO1
    • renal carcinoma antigen NYREN32
    see all
  • 相关性Progerin is a 614 amino acid protein involved in Hutchinson-Gilford progeria syndrome. Progerin is most often generated by a point mutation (C1824T) in the LMNA gene that codes for lamin A and C. This mutation activates a cryptic splice site and gives rise to a form of lamin A with a 50-amino acids internal deletion within the carboxyl-terminal domain of the protein. Approximately 80% of Hutchinson-Gilford progeria syndrome cases carry a single copy of the most common mutation, a silent point mutation, G608G (GGC > GGT), within exon 11 of LMNA gene.
  • 细胞定位Cell Membrane, Cytoplasmic, intermediate filament and Nuclear

Recombinant Rat Progerin protein 图像

  • ab93917 by SDS-PAGE (8% polyacrylamide) and stained with Coomassie Blue.
    Lane 1: MWM
    Lane 2: 4µg ab93917
    Lane 3: 3µg ab93917
    Lane 4: 2µg ab93917
    Lane 5: 1µg ab93917

Recombinant Rat Progerin protein (ab93917)参考文献

ab93917 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab93917.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"