Recombinant大鼠IL17 protein (ab78597)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Rat
    • 序列MAVLIPQSSV CPNAEANNFL QNVKVNLKVL NSLSSKASSR RPSDYLNRST SPWTLSRNED PDRYPSVIWE AQCRHQRCVN AEGKLDHHMN SVLIQQEILV LKREPEKCPF TFRVEKMLVG VGCTCVSSIV RHAS

技术指标

Our Abpromise guarantee covers the use of ab78597 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Biological Activity: ab78597 is fully biologically active when compared to standards via dose-dependent induction of IL6 production in cultured mouse NIH 3T3 fibrolasts. The ED50 for ab78597 in this assay was 30ng/ml.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purity is greater than 97% as determined by reducing and non-reducing SDS-PAGE. Endotoxin level is <0.01ng/ug or <0.1EU/ug. This product is filter sterilised.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 10mM sodium citrate, pH 3.0

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute with sterile water at a concentration of 0.1 mg/ml, which can be further diluted into other aqueous solutions. Reconstituted material should be aliquoted and frozen at -20C. It is recommended to add a carrier protein (0.1% HSA or BSA) for long term storage.

常规信息

  • 别名
    • CTLA 8
    • CTLA-8
    • CTLA8
    • Cytotoxic T lymphocyte associated antigen 8
    • Cytotoxic T lymphocyte associated protein 8
    • Cytotoxic T lymphocyte associated serine esterase 8
    • Cytotoxic T-lymphocyte-associated antigen 8
    • IL 17A
    • IL-17
    • IL-17A
    • IL17
    • IL17_HUMAN
    • Il17a
    • Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8)
    • Interleukin 17A
    • Interleukin-17A
    • Interleukin17
    • Interleukin17A
    • OTTHUMP00000016597
    • OTTMUSP00000046003
    see all
  • 功能Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).
  • 组织特异性Restricted to activated memory T-cells.
  • 序列相似性Belongs to the IL-17 family.
  • 翻译后修饰Found both in glycosylated and nonglycosylated forms.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant rat IL17 protein 图像

  • ab78597 used in Functional Studies.

Recombinant rat IL17 protein (ab78597)参考文献

ab78597 has not yet been referenced specifically in any publications.

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