The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Determined by its ability to chemoattract 293 transfected CXCR2 cells using a concentration range of 10-100 ng/ml, corresponding to a specific activity of 10,000-100,000 units/mg.
% SDS-PAGE. ab125819 is purified by proprietary chromatographic techniques. Purity is greater than 97.0% as determined by RP-HPLC and SDS-PAGE.
Upon reconstitution ab125819 should be stored at 4°C between 2-7 days and for future use below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
pH: 7.40 Constituent: 99% PBS
This product is an active protein and may elicit a biological response in vivo, handle with caution.
It is recommended to reconstitute the lyophilized ab125819 in sterile 18Mcm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
C-X-C motif chemokine 3
C-X-C motif chemokine ligand 3
Chemokine (C X C motif) ligand 3
Chemokine (CXC motif) ligand 3
Cytokine induced neutrophil chemoattractant 2
Dendritic cell inflammatory protein 1
GRO protein gamma
Growth regulated protein gamma
Growth-regulated protein gamma
Macrophage inflammatory protein 2 beta precursor
Macrophage inflammatory protein 2-beta
Melanoma growth stimulatory activity gamma
Small inducible cytokine subfamily B
Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.
Belongs to the intercrine alpha (chemokine CxC) family.
N-terminal processed form GRO-gamma(5-73) is produced by proteolytic cleavage after secretion from peripheral blood monocytes.