Recombinant兔Interferon gamma protein (ab93911)

概述

描述

  • 性质Recombinant
  • 来源Yeast
  • 氨基酸序列
    • 种属Rabbit
    • 序列QDTLTRETEH LKAYLKANTS DVANGGPLFL NILRNWKEES DNKIIQSQIV SFYFKLFDNL KDHEVIKKSM ESIKEDIFVK FFNSNLTKMD DFQNLTRISV DDRLVQRKAV SELSNVLNFL SPKSNLKKRK RSQTLFRGRR ASKY

技术指标

Our Abpromise guarantee covers the use of ab93911 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Purified by Ion-exchange chromatography.
  • 形式Lyophilised
  • 补充说明Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

  • 复溶Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.

常规信息

  • 别名
    • IFG
    • IFI
    • IFN gamma
    • IFN, immune
    • IFN-gamma
    • IFNG
    • IFNG_HUMAN
    • Immune interferon
    • Interferon gamma
    see all
  • 功能Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
  • 组织特异性Released primarily from activated T lymphocytes.
  • 疾病相关In Caucasians, genetic variation in IFNG is associated with the risk of aplastic anemia (AA) [MIM:609135]. AA is a rare disease in which the reduction of the circulating blood cells results from damage to the stem cell pool in bone marrow. In most patients, the stem cell lesion is caused by an autoimmune attack. T-lymphocytes, activated by an endogenous or exogenous, and most often unknown antigenic stimulus, secrete cytokines, including IFN-gamma, which would in turn be able to suppress hematopoiesis.
  • 序列相似性Belongs to the type II (or gamma) interferon family.
  • 翻译后修饰Proteolytic processing produces C-terminal heterogeneity, with proteins ending alternatively at Gly-150, Met-157 or Gly-161.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Rabbit Interferon gamma protein (ab93911)参考文献

ab93911 has not yet been referenced specifically in any publications.

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