Recombinant PKC delta protein (ab27714)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus

技术指标

Our Abpromise guarantee covers the use of ab27714 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

  • 形式Liquid
  • 补充说明Not enzymatically active. The protein is suspended in SDS/mercaptoethanol sample buffer with a bromphenol blue dye marker.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Constituents: 0.02% Bromophenol blue, 5% Beta mercaptoethanol, 2% SDS

常规信息

  • 别名
    • CVID9
    • D14Ertd420e
    • Kinase PKC delta
    • KPCD
    • KPCD_HUMAN
    • MAY 1
    • MAY1
    • MGC49908
    • nPKC delta
    • nPKC-delta
    • PCKd
    • PKC d
    • PKC delta
    • PKCD
    • PKCdelta
    • PRKC D
    • PRKC delta
    • Prkcd
    • Protein Kinase C delta
    • Protein kinase C delta type
    • Protein kinase C delta VIII
    • Protein Kinase Cdelta
    • Tyrosine protein kinase PRKCD
    see all
  • 功能This is calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. May play a role in antigen-dependent control of B-cell function. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
  • 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
    Contains 1 AGC-kinase C-terminal domain.
    Contains 1 C2 domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • 结构域The C1 domain, containing the phorbol ester/DAG-type region 1 (C1A) and 2 (C1B), is the diacylglycerol sensor.
    The C2 domain is a non-calcium binding domain. It binds proteins containing phosphotyrosine in a sequence-specific manner.
  • 翻译后修饰Phosphorylated on Thr-507, within the activation loop. Autophosphorylated and/or phosphorylated. Although the Thr-507 phosphorylation occurs it is not a prerequisite for enzymatic activity.
  • 细胞定位Cytoplasm. Membrane.
  • Information by UniProt

Recombinant PKC delta protein (ab27714)参考文献

ab27714 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab27714.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"