Recombinant猪LD78 beta protein (ab87908)

概述

描述

  • 性质
    Recombinant
  • 来源
    Saccharomyces cerevisiae
  • 氨基酸序列
    • 种属
      Pig
    • 序列
      APLGADTPTA CCFSYTSRQL PRKFVADYFE TSSQCSKPGV IFQTKKGREV CANPEDAWVQ EYISDLELNA

技术指标

Our Abpromise guarantee covers the use of ab87908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    The biological activity of ab87908 was determined in a chemotaxis assay using a Boyden chamber with freshly isolated swine PBMC monocytes using a Percoll gradient enrichment method. Biological activity typically peaks at 100 ng/mL.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度
    > 95 % SDS-PAGE.
    ab87908 was purified using Ion-exchange chromatography
  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Trehalose, 1X PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C.

常规信息

  • 别名
    • 464.2
    • C C motif chemokine 3 like 1
    • CCL3L1
    • CCL3L3
    • Chemokine (C C motif) ligand 3 like 1
    • Chemokine (C C motif) ligand 3 like 3
    • Chemokine (C C motif) ligand 3 like, centromeric
    • chemokine (CC motif) ligand 3 like 1
    • CL3L1_HUMAN
    • D17S1718
    • G0/G1 switch regulatory protein 19-2
    • G0S19-2
    • LD78
    • LD78 beta(1-70)
    • LD78-beta(1-70)
    • LD78-beta(5-70)
    • LD78BETA
    • MGC104178
    • MGC12815
    • MGC182017
    • MIP1AP
    • PAT 464.2
    • SCYA3L
    • SCYA3L1
    • Small inducible cytokine A3 like 1 precursor
    • Small-inducible cytokine A3-like 1
    • Tonsillar lymphocyte LD78 beta
    • Tonsillar lymphocyte LD78 beta protein
    see all
  • 功能
    Chemotactic for lymphocytes and monocytes. Is a ligand for CCR1, CCR3 and CCR5. Is an inhibitor of HIV-1-infection. The processed form LD78-beta(3-70) shows a 20-fold to 30-fold higher chemotactic activity and is a very potent inhibitor of HIV-1-infection. LD78-beta(3-70) is also a ligand for CCR1, CCR3 and CCR5.
  • 序列相似性
    Belongs to the intercrine beta (chemokine CC) family.
  • 翻译后修饰
    The N-terminal processed forms LD78-beta(3-70) and LD78-beta(5-70) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. The cleavage to yield LD78-beta(3-70) is probably achieved by DPP4.
  • 细胞定位
    Secreted.
  • Information by UniProt

文献

ab87908 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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