重组人PDGF AA蛋白(ab9702)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
描述
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产品名称
重组人PDGF AA蛋白
参阅全部 PDGF AA 蛋白酶 -
纯度
> 98 % SDS-PAGE.
Sterile filtered Greater than 98% pure by HPLC analyses. Endotoxin level is less than 0.1 ng per g (1EU/g). -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Human -
预测分子量
24 kDa
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技术指标
Our Abpromise guarantee covers the use of ab9702 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Functional Studies
SDS-PAGE
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形式
Lyophilized -
补充说明
The biological activity is determined by the dose-dependent stimulation of the proliferation of BALB/c 3T3 cells, is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituent: 0.06% Acetic acid
This product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶For lot specific reconstitution information please contact our Scientific Support Team.
常规信息
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别名
- PDGF A
- PDGF A chain
- PDGF subunit A
see all -
功能
Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound. -
序列相似性
Belongs to the PDGF/VEGF growth factor family. -
结构域
The long form contains a basic insert which acts as a cell retention signal. -
细胞定位
Secreted. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab9702 被引用在 3 文献中.
- Wang A et al. miR-29a-5p/STAT3 Positive Feedback Loop Regulates TETs in Colitis-Associated Colorectal Cancer. Inflamm Bowel Dis 26:524-533 (2020). PubMed: 31750910
- Katz DB et al. An immortalized human adipose-derived stem cell line with highly enhanced chondrogenic properties. Biochem Biophys Res Commun 530:252-258 (2020). PubMed: 32828295
- Gomez JA et al. Ventral tegmental area astrocytes orchestrate avoidance and approach behavior. Nat Commun 10:1455 (2019). PubMed: 30926783