重组Mycobacterium tuberculosis TB Ag85A蛋白(ab124604)

概述

  • 产品名称
    重组Mycobacterium tuberculosis TB Ag85A蛋白
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus infected BTI-TN-5B1-4 cells
  • 氨基酸序列
    • Accession
    • 种属
      Mycobacterium tuberculosis
    • 序列
      ADPAFSRPGL PVEYLQVPSP SMGRDIKVQF QSGGANSPAL YLLDGLRAQD DFSGWDINTP AFEWYDQSGL SVVMPVGGQS SFYSDWYQPA CGKAGCQTYK WETFLTSELP GWLQANRHVK PTGSAVVGLS MAASSALTLA IYHPQQFVYA GAMSGLLDPS QAMGPTLIGL AMGDAGGYKA SDMWGPKEDP AWQRNDPLLN VGKLIANNTR VWVYCGNGKP SDLGGNNLPA KFLEGFVRTS NIKFQDAYNA GGGHNGVFDF PDSGTHSWEY WGAQLNAMKP DLQRALGATP NTGPAPQGAHHHHHH
    • 分子量
      33 kDa including tags
    • 氨基酸
      43 to 338
    • 标签
      His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124604 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 内毒素水平
    < 1.000 Eu/µg
  • 纯度
    > 95 % SDS-PAGE.
    ab124604 is purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

常规信息

  • 别名
    • 85 A
    • 85A
    • Ag85A
    • Antigen 85 A
    • Antigen 85 complex A
    • Antigen 85A
    • Fbp A
    • FbpA
    • Fibronectin binding protein A
    • Mpt 44
    • Mpt44
    • Mycobacterium tuberculosis antigen 85A
    • Mycolyl transferase 85 A
    • Mycolyl transferase 85A
    • Rv3804c
    • Secreted antigen Ag85A
    see all
  • 相关性
    Mycobacterium tuberculosis antigen 85 is a complex of three related gene products of 30-31 kDa, Ag85A, B and C. These proteins are responsible for the high affinity of mycobacteria to fibronectin. All three proteins possesses a mycolyltransferase activity - which is required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity. Thus all three proteins are involved in the final stages of mycobacterial cell wall assembly.
  • 细胞定位
    Secreted; cell wall. Cytoplasm

图片

  • 15% SDS-PAGE showing ab124604 (3 µg).

文献

This product has been referenced in:
  • Mancha-Agresti P  et al. Recombinant Invasive Lactococcus lactis Carrying a DNA Vaccine Coding the Ag85A Antigen Increases INF-?, IL-6, and TNF-a Cytokines after Intranasal Immunization. Front Microbiol 8:1263 (2017). Functional Studies ; Mouse . Read more (PubMed: 28744263) »

See 1 Publication for this product

客户评价及客户问答

Thank you for your inquiry.
Please find below the answers to your questions:

1.
I am happy to confirm that this protein (ab124604)is Antigen 85 sub unit A.

2.
a) ab73632 is the full length protein (aa 1 to 325)
b...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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