Recombinant小鼠PIM3 protein (ab125561)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionP58750
    • 种属Mouse
    • 分子量63 kDa including tags
    • 氨基酸1 to 326

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技术指标

Our Abpromise guarantee covers the use of ab125561 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性The specific activity of ab125561 is 785 nmol/min/mg.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 纯度> 90 % Densitometry.
    ab125561 is >90% pure.
  • 形式Liquid
  • 补充说明

    ab204879 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 25% Glycerol, 0.88% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Kid 1
    • Kid1
    • Kinase induced by depolarization
    • ONCOGENE PIM3
    • PIM 3
    • Pim 3 oncogene
    • Pim-3 proto-oncogene, serine/threonine kinase
    • PIM3
    • Pim3 oncogene
    • PIM3_HUMAN
    • Protein kinase Kid 1
    • Protein kinase Kid1
    • Serine/threonine kinase Pim 3
    • Serine/threonine kinase Pim3
    • Serine/threonine protein kinase Pim 3
    • Serine/threonine protein kinase Pim3
    • Serine/threonine-protein kinase Pim-3
    see all
  • 功能Able to phosphorylate CDKN1B in vitro. Involved in cell cycle progression and suppression of apoptosis. Implicated in proliferation of human hepatoma cell lines.
  • 组织特异性Widely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues. Expressed in colon cancer samples, particularly at the less advanced stages of cancer development.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
    Contains 1 protein kinase domain.
  • Information by UniProt

Recombinant mouse PIM3 protein 图像

  • The specific activity of ab125561 was determined to be 785 nmol/min/mg.
  • SDS PAGE analysis of ab125561 (PIM3 protein).

Recombinant mouse PIM3 protein (ab125561)参考文献

ab125561 has not yet been referenced specifically in any publications.

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