Recombinant小鼠PAK3 protein (ab61414)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • 种属Mouse

技术指标

Our Abpromise guarantee covers the use of ab61414 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Specific activity: 259 nmol/min/mg.
  • 应用

    Functional Studies

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    ab43614 (Human Myelin Basic Protein full length protein) can be utilized as a substrate for assessing Kinase activity

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Beta PAK
    • bPAK
    • CDKN1A
    • hPAK3
    • Mental retardation X linked 30
    • MRX30
    • MRX47
    • Oligophrenin 3
    • OPHN3
    • p21 (CDKN1A) activated kinase 3
    • p21 activated kinase 3
    • p21 CDKN1A activated kinase 3
    • P21 protein (Cdc42/Rac) activated kinase 3
    • PAK-3
    • PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
    • PAK3beta
    • Pak65alpha
    • Pak65beta
    • Serine threonine protein kinase PAK 3
    • Stk4
    see all
  • 相关性PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. PAK3 forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. It may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in this gene has been linked to nonsyndromic X-linked mental retardation.
  • 细胞定位Cytoplasmic

Recombinant mouse PAK3 protein 图像

Recombinant mouse PAK3 protein (ab61414)参考文献

ab61414 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"