Recombinant小鼠PAI1 + PLAT protein (ab92709)

概述

描述

  • 性质Recombinant
  • 来源Insect cells
  • 氨基酸序列
    • 种属Mouse

技术指标

Our Abpromise guarantee covers the use of ab92709 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    Mouse sc-tPA is reacted with an excess of Mouse PAI1 stable mutant at physiological pH. The resulting 1:1 molar complex is purified from the remaining PAI1 by affinity chromatography with immobilized antibodies to Mouse tPA.
  • 形式Liquid
  • 补充说明Solubility: > 2 mg/mL
    Spectrophotometric Data: ε0.1%=1.5
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.4M HEPES, 0.1M Sodium chloride, pH 7.4

常规信息

  • 别名
    • Alteplase
    • PAI 1
    • PLANH1
    • Plasminogen activator inhibitor 1
    • PLAT
    • Reteplase
    • t PA
    • t plasminogen activator
    • tPA
    see all
  • 相关性PAI1 acts as "bait" for tissue plasminogen activator (TPA), urokinase, and protein C. Its rapid interaction with TPA may function as a major control point in the regulation of fibrinolysis. TPA: This converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events.
  • 细胞定位Secreted protein; extracellular space.

Recombinant Mouse PAI1 + PLAT protein 图像

  • 10% SDS-PAGE
    Lane 1: Mouse PAI1, Non-reduced
    Lane 2: Mouse tPA, Non-reduced
    Lane 3: Mouse PAI1 + tPA, Non-reduced
    Lane 4: Mouse PAI1 + tPA, Reduced
    Lane 5: Mouse PAI1, Reduced
    Lane 6: Mouse tPA, Reduced
    Lane 7: Prestained standard

Recombinant Mouse PAI1 + PLAT protein (ab92709)参考文献

ab92709 has not yet been referenced specifically in any publications.

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