Recombinant小鼠MYL9 protein (ab60014)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Mouse

技术指标

Our Abpromise guarantee covers the use of ab60014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 形式
    Liquid
  • 补充说明

    ab60014 (Mouse MYL9 full length protein) can be utilized as a substrate for the following active protein Kinases:

     

    ab55674 (Active human Myosin light chain kinase protein fragment)
    ab84799 (Active human MYLK3 full length protein)
    ab84800 (Active human MYLK2 full length protein)
    ab89742 (Active human DAP Kinase 2 full length protein)
    ab190995 (Active human MYLK4 full length protein)

     

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • 20 kDa myosin light chain
    • Human 20kDa myosin light chain (MLC2) mRNA complete cds
    • LC20
    • MGC3505
    • MLC 2
    • MLC-2C
    • MLC2
    • MLY 9
    • MRLC1
    • MYL9
    • MYL9_HUMAN
    • Myosin light chain 9 regulatory
    • Myosin light polypeptide 9 regulatory
    • myosin regulatory light chain 1
    • Myosin regulatory light chain 2
    • Myosin regulatory light chain 2 smooth muscle isoform
    • Myosin regulatory light chain 9
    • Myosin regulatory light chain MRLC1
    • Myosin regulatory light polypeptide 9
    • Myosin RLC
    • Myosin vascular smooth muscle light chain 2
    • MYRL2
    • OTTHUMP00000030857
    • smooth muscle isoform
    see all
  • 功能
    Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
  • 组织特异性
    Smooth muscle tissues and in some, but not all, nonmuscle cells.
  • 序列相似性
    Contains 3 EF-hand domains.
  • 翻译后修饰
    Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge.
  • Information by UniProt

图片

  • ab60014 on SDS-PAGE.

文献

ab60014 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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