Recombinant小鼠IL2 protein (ab119728)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 分子量
      17 kDa
    • 氨基酸
      21 to 169

技术指标

Our Abpromise guarantee covers the use of ab119728 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    The ED50 range is 0.1-0.4 ng/ml, as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells.
  • 应用

    SDS-PAGE

    HPLC

    Functional Studies

  • 纯度
    > 98 % SDS-PAGE.
    Purity: >98% by SDS-PAGE and HPLC analysis. Endotoxin level is <0.1 ng per µg of IL2.
  • 形式
    Lyophilised
  • 补充说明
    ab119728 is best-stored desiccated.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -80°C. Avoid freeze / thaw cycle. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA).

    pH: 4.00
    Constituent: 0.26% Sodium citrate

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶
    Centrifuge the vial prior to opening. Reconstitute in 100 mM AcOH to a concentration of 0.1-1 µg/µl to regain full activity. The solution can then be diluted into other aqueous buffers.

常规信息

  • 别名
    • Aldesleukin
    • IL 2
    • IL-2
    • IL2
    • IL2_HUMAN
    • Interleukin 2
    • Interleukin-2
    • Involved in regulation of T cell clonal expansion
    • Lymphokine
    • OTTHUMP00000164090
    • POIL2
    • T Cell Growth Factor
    • T-cell growth factor
    • TCGF
    see all
  • 功能
    Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells.
  • 疾病相关
    Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.
  • 序列相似性
    Belongs to the IL-2 family.
  • 细胞定位
    Secreted.
  • Information by UniProt

Recombinant mouse IL2 protein (ab119728)参考文献

ab119728 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119728.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册