Recombinant小鼠Hsp70 protein (ab113187)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 分子量
      70 kDa
    • 氨基酸
      1 to 641

技术指标

Our Abpromise guarantee covers the use of ab113187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    ATPase activity assay (positive) but there is not quantification of activity
  • 应用

    Western blot

    SDS-PAGE

    Functional Studies

  • 纯度
    > 85 % SDS-PAGE.
    ab113187 is purified by multi-step chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.15% Glutathione, 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • DnaK type molecular chaperone HSP70 1
    • Epididymis secretory protein Li 103
    • FLJ54303
    • FLJ54370
    • FLJ54392
    • FLJ54408
    • FLJ75127
    • Heat shock 70 kDa protein 1
    • Heat shock 70 kDa protein 1/2
    • Heat shock 70 kDa protein 1A/1B
    • Heat shock 70kDa protein 1A
    • Heat shock 70kDa protein 1B
    • Heat shock induced protein
    • HEL S 103
    • HSP70 1
    • HSP70 1B
    • HSP70 2
    • HSP70-1/HSP70-2
    • HSP70-1A
    • HSP70.1
    • HSP70.1/HSP70.2
    • HSP70I
    • HSP71_HUMAN
    • HSP72
    • HSPA1
    • HSPA1A
    • HSPA1B
    see all
  • 功能
    In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • 组织特异性
    HSPA1B is testis-specific.
  • 序列相似性
    Belongs to the heat shock protein 70 family.
  • 细胞定位
    Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

图片

  • SDS-PAGE showing ab113187 (1µg).
  • Lane 1: MWM
    Lane 2: 100 ng ab113187
    Lane 3: 50 ng E. coli DnaK Protein

    Left: probed with Hsp70 mAb at 1.0 µg/ml.
    Right: probed with DnaK mAb at 1.0 µg/ml.

文献

ab113187 has not yet been referenced specifically in any publications.

客户评价及客户问答

This protein, ab113187, does not have a tag.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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