Recombinant小鼠Hsp70 protein (ab113187)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ61696
    • 种属Mouse
    • 分子量70 kDa
    • 氨基酸1 to 641

技术指标

Our Abpromise guarantee covers the use of ab113187 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性ATPase activity assay (positive) but there is not quantification of activity
  • 应用

    Western blot

    SDS-PAGE

    Functional Studies

  • 纯度> 85 % SDS-PAGE.
    ab113187 is purified by multi-step chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.15% Glutathione, 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • DnaK type molecular chaperone HSP70 1
    • Epididymis secretory protein Li 103
    • FLJ54303
    • FLJ54370
    • FLJ54392
    • FLJ54408
    • FLJ75127
    • Heat shock 70 kDa protein 1
    • Heat shock 70 kDa protein 1/2
    • Heat shock 70 kDa protein 1A/1B
    • Heat shock 70kDa protein 1A
    • Heat shock 70kDa protein 1B
    • Heat shock induced protein
    • HEL S 103
    • HSP70 1
    • HSP70 1B
    • HSP70 2
    • HSP70-1/HSP70-2
    • HSP70-1A
    • HSP70.1
    • HSP70.1/HSP70.2
    • HSP70I
    • HSP71_HUMAN
    • HSP72
    • HSPA1
    • HSPA1A
    • HSPA1B
    see all
  • 功能In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
  • 组织特异性HSPA1B is testis-specific.
  • 序列相似性Belongs to the heat shock protein 70 family.
  • 细胞定位Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
  • Information by UniProt

Recombinant mouse Hsp70 protein 图像

  • SDS-PAGE showing ab113187 (1µg).
  • Lane 1: MWM
    Lane 2: 100 ng ab113187
    Lane 3: 50 ng E. coli DnaK Protein

    Left: probed with Hsp70 mAb at 1.0 µg/ml.
    Right: probed with DnaK mAb at 1.0 µg/ml.

Recombinant mouse Hsp70 protein (ab113187)参考文献

ab113187 has not yet been referenced specifically in any publications.

Product Wall

This protein, ab113187, does not have a tag.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"