重组小鼠EPO蛋白(Fc Chimera) (ab170076)
Key features and details
- Expression system: Insect cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
描述
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产品名称
重组小鼠EPO蛋白(Fc Chimera)
参阅全部 EPO 蛋白酶 -
生物活性
ED50 < 5 ng/ml as determined in a cell proliferation assay using Human TF-1 erythroleukemia cells.
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纯度
> 95 % SDS-PAGE.
ab170076 is purified by chromatography, sterile filtered and lyophilized. -
表达系统
Insect cells -
Accession
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蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
序列
APPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYA WKRMEVEEQAIEVWQGLSLLSEAILQAQALLANSSQPPETLQLHIDKAIS GLRSLTSLLRVLGAQKELMSPPDTTPPAPLRTLTVDTFCKLFRVYANFLR GKLKLYTGEVCRRGDR -
预测分子量
49 kDa -
氨基酸
27 to 192
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技术指标
Our Abpromise guarantee covers the use of ab170076 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
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形式
Lyophilized -
补充说明
Produced using non-baculovirus insect cells.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -80°C.
pH: 7.4
Constituent: 100% PBSThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Add 0.5ml deionized water. Aliquot and freeze unused portion.
常规信息
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别名
- EP
- EPO
- EPO alpha
see all -
相关性
Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. -
细胞定位
Secreted
图片
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (1)
ab170076 被引用在 1 文献中.
- Ferrao RD et al. Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation. Elife 7:N/A (2018). PubMed: 30044226