重组小鼠DR6蛋白(ab109063)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level: < 0.100 Eu/µg
- Suitable for: SDS-PAGE
描述
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产品名称
重组小鼠DR6蛋白
参阅全部 DR6 蛋白酶 -
纯度
> 95 % SDS-PAGE. -
内毒素水平
< 0.100 Eu/µg -
表达系统
HEK 293 cells -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Mouse -
预测分子量
80 kDa -
氨基酸
42 to 348
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技术指标
Our Abpromise guarantee covers the use of ab109063 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
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形式
Lyophilized -
补充说明
PBS containing at least 0.1% BSA should be used for further dilutions. -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C.
Constituent: PBS
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复溶Reconstitute with 50 µl sterile water.
常规信息
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别名
- TNFRSF 21
- BM 018
- BM018
see all -
功能
May activate NF-kappa-B and promote apoptosis. May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). -
组织特异性
Highly expressed in heart, brain, placenta, pancreas, lymph node, thymus and prostate. Detected at lower levels in lung, skeletal muscle, kidney, testis, uterus, small intestine, colon, spleen, bone marrow and fetal liver. Very low levels were found in adult liver and peripheral blood leukocytes. -
序列相似性
Contains 1 death domain.
Contains 4 TNFR-Cys repeats. -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab109063 尚未被引用在任何文献中。