概述
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产品名称Recombinant小鼠DLK protein (Fc fragment)
参阅全部 DLK 蛋白酶 -
蛋白长度Protein fragment
描述
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性质Recombinant
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来源HEK 293 cells
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氨基酸序列
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Accession
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种属Mouse
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分子量75 kDa
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氨基酸1 to 305
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额外的序列信息Fused with the Fc region of Human IgG1 at the C-terminus.
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技术指标
Our Abpromise guarantee covers the use of ab108574 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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生物活性Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
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应用
Functional Studies
SDS-PAGE
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内毒素水平< 0.100 Eu/µg
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纯度> 90 % SDS-PAGE.
ab108574 is 0.2µm filtered -
形式Liquid
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补充说明Working aliquots are stable for up to 3 months when stored at -20°C. Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: None
Constituents: PBS
常规信息
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别名
- Adipocyte differentiation inhibitor protein
- Brevideltin
- Delta like 1 homolog
see all -
功能May have a role in neuroendocrine differentiation.
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组织特异性Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
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序列相似性Contains 6 EGF-like domains.
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翻译后修饰N- and O-glycosylated.
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细胞定位Membrane.
- Information by UniProt
Recombinant Mouse DLK protein (Fc fragment) 图像
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Functional Studies - Mouse DLK protein fragment:Fc portion of human IgG (ab108574)Induction of SOX-9 with the treatment of recombinant mouse DLK-Fc (ab108574).
A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5µg/ml of ab108574 as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-rabbit Sox-9 and anti-rabbit GAPDH.1=0 min; 2=10 min; 3=30 min; 4=1 h; 5=2 h; 6=3 h; 7=4 h; 8=24 h.
Recombinant Mouse DLK protein (Fc fragment) (ab108574)参考文献
ab108574 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"