Recombinant小鼠DLK protein (Fc fragment) (ab108574)

概述

描述

  • 性质
    Recombinant
  • 来源
    HEK 293 cells
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 分子量
      75 kDa
    • 氨基酸
      1 to 305
    • 额外的序列信息
      Fused with the Fc region of Human IgG1 at the C-terminus.

技术指标

Our Abpromise guarantee covers the use of ab108574 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平
    < 0.100 Eu/µg
  • 纯度
    > 90 % SDS-PAGE.
    ab108574 is 0.2µm filtered
  • 形式
    Liquid
  • 补充说明
    Working aliquots are stable for up to 3 months when stored at -20°C. Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

常规信息

  • 别名
    • Adipocyte differentiation inhibitor protein
    • Brevideltin
    • Delta like 1 homolog
    • Delta like homolog
    • Delta like protein
    • Delta1
    • DLK
    • DLK 1
    • DLK-1
    • DLK1
    • DLK1_HUMAN
    • FA 1
    • FA1
    • Fetal antigen 1
    • pG2
    • Preadipocyte factor 1
    • Pref
    • Pref 1
    • Pref1
    • Protein delta homolog 1
    • Secredeltin
    • ZOG
    see all
  • 功能
    May have a role in neuroendocrine differentiation.
  • 组织特异性
    Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.
  • 序列相似性
    Contains 6 EGF-like domains.
  • 翻译后修饰
    N- and O-glycosylated.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • Induction of SOX-9 with the treatment of recombinant mouse DLK-Fc (ab108574).
    A mouse preadpipocyte cell line, 3T3L1, was stimulated with 5µg/ml of ab108574 as in indicated time points and each cell lysate was prepared and subjected to western blot by using anti-rabbit Sox-9 and anti-rabbit GAPDH.

    1=0 min; 2=10 min; 3=30 min; 4=1 h; 5=2 h; 6=3 h; 7=4 h; 8=24 h.

     

文献

ab108574 has not yet been referenced specifically in any publications.

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