Recombinant小鼠CD105 protein (ab123754)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus infected Sf9 cells
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 序列
      MDRGVLPLPITLLFVIYSFVPTTGLAERVGCDLQPVDPTRGEVTFTTSQV SEGCVAQAANAVREVHVLFLDFP GMLSHLELTLQASKQNGTETQEVFL VLVSNKNVFVKFQAPEIPLHLAYDSSLVIFQGQPRVNITVLPSLTSRK QILDWAATKGAITSIAALDDPQSIVLQLGQDPKAPFLCLPEAHKDMGATL EWQPRAQTPVQSCRLEGVSGHK EAYILRILPGSEAGPRTVTVMMELSC TSGDAILILHGPPYVSWFIDINHSMQILTTGEYSVKIFPGSKVKGVELP DTPQGLIAEARKLNASIVTSFVELPLVSNVSLRASSCGGVFQTTPAPVV TTPPKDTCSPVLLMSLIQPKCGNQ VMTLALNKKHVQTLQCTITGLTFW DSSCQAEDTDDHLVLSSAYSSCGMKVTAHVVSNEVIISFPSGSPPLRK KVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQAFVQVSVSPLTSEVTV QLDSCHLDLGPEGDMVELIQSRT AKGSCVTLLSPSPEGDPRFSFLLRV YMVPTPTAGTLSCNLALRPSTLSQEVYKTVSMRLNIVSPDLS
    • 分子量
      61 kDa
    • 氨基酸
      28 to 578
    • 标签
      His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    HPLC

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    ab123754 is purified by proprietary chromatographic techniques. Purity is greater than 95% as determined by HPLC and SDS-PAGE.
  • 形式
    Lyophilised
  • 补充说明
    Centrifuge the vial prior to opening.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20ºC.

  • 复溶
    Centrifuge the vial prior to opening. Reconstitute in sterile PBS to a concentration of 100 µg/ml. This solution can then be diluted into other aqueous buffers. Reconstituted ab123754 should be stored at 4°C for 2-7 days and at -20°C for future use. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA). Avoid freeze/thaw cycles.

常规信息

  • 别名
    • AI528660
    • AI662476
    • CD 105
    • CD105
    • CD105 antigen
    • EGLN_HUMAN
    • END
    • Endoglin
    • Eng
    • FLJ41744
    • HHT1
    • ORW
    • ORW1
    • Osler Rendu Weber syndrome 1
    • RP11 228B15.2
    • S-endoglin
    • SN6
    see all
  • 功能
    Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性
    Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关
    Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位
    Membrane.
  • Information by UniProt

文献

ab123754 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab123754.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册