Recombinant小鼠CD105 protein (ab123754)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ63961
    • 种属Mouse
    • 序列MDRGVLPLPITLLFVIYSFVPTTGLAERVGCDLQPVDPTRGEVTFTTSQV SEGCVAQAANAVREVHVLFLDFP GMLSHLELTLQASKQNGTETQEVFL VLVSNKNVFVKFQAPEIPLHLAYDSSLVIFQGQPRVNITVLPSLTSRK QILDWAATKGAITSIAALDDPQSIVLQLGQDPKAPFLCLPEAHKDMGATL EWQPRAQTPVQSCRLEGVSGHK EAYILRILPGSEAGPRTVTVMMELSC TSGDAILILHGPPYVSWFIDINHSMQILTTGEYSVKIFPGSKVKGVELP DTPQGLIAEARKLNASIVTSFVELPLVSNVSLRASSCGGVFQTTPAPVV TTPPKDTCSPVLLMSLIQPKCGNQ VMTLALNKKHVQTLQCTITGLTFW DSSCQAEDTDDHLVLSSAYSSCGMKVTAHVVSNEVIISFPSGSPPLRK KVQCIDMDSLSFQLGLYLSPHFLQASNTIELGQQAFVQVSVSPLTSEVTV QLDSCHLDLGPEGDMVELIQSRT AKGSCVTLLSPSPEGDPRFSFLLRV YMVPTPTAGTLSCNLALRPSTLSQEVYKTVSMRLNIVSPDLS
    • 分子量61 kDa
    • 氨基酸28 to 578
    • 标签His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab123754 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    HPLC

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab123754 is purified by proprietary chromatographic techniques. Purity is greater than 95% as determined by HPLC and SDS-PAGE.
  • 形式Lyophilised
  • 补充说明Centrifuge the vial prior to opening.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20ºC.

  • 复溶Centrifuge the vial prior to opening. Reconstitute in sterile PBS to a concentration of 100 µg/ml. This solution can then be diluted into other aqueous buffers. Reconstituted ab123754 should be stored at 4°C for 2-7 days and at -20°C for future use. For long term storage it is recommended to add a carrier protein (0.1 % HSA or BSA). Avoid freeze/thaw cycles.

常规信息

  • 别名
    • AI528660
    • AI662476
    • CD 105
    • CD105
    • CD105 antigen
    • EGLN_HUMAN
    • END
    • Endoglin
    • Eng
    • FLJ41744
    • HHT1
    • ORW
    • ORW1
    • Osler Rendu Weber syndrome 1
    • RP11 228B15.2
    • S-endoglin
    • SN6
    see all
  • 功能Major glycoprotein of vascular endothelium. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.
  • 组织特异性Endoglin is restricted to endothelial cells in all tissues except bone marrow.
  • 疾病相关Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1) [MIM:187300, 108010]; also known as Osler-Rendu-Weber syndrome 1 (ORW1). HHT1 is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations; all secondary manifestations of the underlying vascular dysplasia. Although the first symptom of HHT1 in children is generally nose bleed, there is an important clinical heterogeneity.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Mouse CD105 protein (ab123754)参考文献

ab123754 has not yet been referenced specifically in any publications.

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