Recombinant小鼠BCMA protein (ab109162)

概述

描述

  • 性质
    Recombinant
  • 来源
    HEK 293 cells
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 分子量
      35 kDa
    • 氨基酸
      1 to 46

技术指标

Our Abpromise guarantee covers the use of ab109162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平
    < 0.100 Eu/µg
  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • 补充说明
    PBS containing at least 0.1 % BSA should be used for further dilutions. Binds Mouse and Human BAFF and APRIL. Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Constituent: 99% PBS

  • 复溶
    Reconstitute with 50 µl sterile water.

常规信息

  • 别名
    • B cell maturation antigen
    • B cell maturation factor
    • B cell maturation protein
    • B-cell maturation protein
    • BCM
    • BCMA
    • CD269
    • CD269 antigen
    • TNFRSF17
    • TNR17_HUMAN
    • Tumor necrosis factor receptor superfamily member 17
    see all
  • 功能
    Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 组织特异性
    Expressed in mature B-cells, but not in T-cells or monocytes.
  • 疾病相关
    Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 序列相似性
    Contains 1 TNFR-Cys repeat.
  • 细胞定位
    Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt

Recombinant Mouse BCMA protein (ab109162)参考文献

ab109162 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab109162.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册