- 来源HEK 293 cells
- 分子量35 kDa
- 氨基酸1 to 46
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 生物活性Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
- 内毒素水平< 0.100 Eu/µg
- 纯度> 95
- 补充说明PBS containing at least 0.1 % BSA should be used for further dilutions. Binds Mouse and Human BAFF and APRIL.
Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
Concentration information loading...
Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.
Constituent: 99% PBS
- 复溶Reconstitute with 50 µl sterile water.
- B cell maturation antigen
- B cell maturation factor
- B cell maturation protein
- 功能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
- 组织特异性Expressed in mature B-cells, but not in T-cells or monocytes.
- 疾病相关Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
- 序列相似性Contains 1 TNFR-Cys repeat.
- 细胞定位Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
Information by UniProt
Recombinant Mouse BCMA protein (ab109162)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"