Recombinant小鼠BCMA protein (ab109162)

概述

描述

  • 性质Recombinant
  • 来源HEK 293 cells
  • 氨基酸序列
    • AccessionO88472
    • 种属Mouse
    • 分子量35 kDa
    • 氨基酸1 to 46

技术指标

Our Abpromise guarantee covers the use of ab109162 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • 补充说明PBS containing at least 0.1 % BSA should be used for further dilutions. Binds Mouse and Human BAFF and APRIL. Blocks the binding of Mouse BAFF and Human APRIL to their receptors BCMA and TACI.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Constituent: 99% PBS

  • 复溶Reconstitute with 50 µl sterile water.

常规信息

  • 别名
    • B cell maturation antigen
    • B cell maturation factor
    • B cell maturation protein
    • B-cell maturation protein
    • BCM
    • BCMA
    • CD269
    • CD269 antigen
    • TNFRSF17
    • TNR17_HUMAN
    • Tumor necrosis factor receptor superfamily member 17
    see all
  • 功能Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
  • 组织特异性Expressed in mature B-cells, but not in T-cells or monocytes.
  • 疾病相关Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
  • 序列相似性Contains 1 TNFR-Cys repeat.
  • 细胞定位Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
  • Information by UniProt

Recombinant Mouse BCMA protein (ab109162)参考文献

ab109162 has not yet been referenced specifically in any publications.

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