Recombinant小鼠AHA1 protein (ab111143)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 分子量
      38 kDa
    • 氨基酸
      1 to 338
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab111143 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性
    2uM ab111143 generated a 9-fold ATPase activation of 2uM Hsp90 (His-tagged Hsp90 beta) in 33mM Hepes pH7.2, 30mM NaCl, 5mM MgCl2, 1mM DTT, 1.5mM ATP in a 100ul reaction at 37 degrees celcius (this is an enzyme-linked ATP regeneration assay tracking loss of NADH absorbance at 340nm).
  • 应用

    Functional Studies

    Western blot

  • 纯度
    > 90 % SDS-PAGE.

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

    pH: 7.20
    Constituents: 0.88% Sodium chloride, 0.002% DTT, 50% Glycerol, 0.378% Tris HCl

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Activator of 90 kDa heat shock protein ATPase homolog 1
    • Activator of heat shock 90kDa protein ATPase homolog 1
    • AHA 1
    • AHA1
    • AHSA 1
    • Ahsa1
    • AHSA1_HUMAN
    • C14orf3
    • HSPC322
    • p38
    see all
  • 功能
    Cochaperone that stimulates HSP90 ATPase activity (By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
  • 组织特异性
    Expressed in numerous tissues, including brain, heart, skeletal muscle and kidney and, at lower levels, liver and placenta.
  • 序列相似性
    Belongs to the AHA1 family.
  • 细胞定位
    Cytoplasm > cytosol. Endoplasmic reticulum. May transiently interact with the endoplasmic reticulum.
  • Information by UniProt

Recombinant mouse AHA1 protein (ab111143)参考文献

ab111143 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111143.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册