Recombinant MNDA protein (ab117166)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP41218
    • 序列MGSSHHHHHH SSGLVPRGSH MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV
    • 分子量48 kDa including tags
    • 氨基酸1 to 407
    • 标签His tag N-Terminus
    • 额外的序列信息MNDA Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 427 amino acids (1-407 a.a.) and having a molecular mass of 47.9 kDa.

技术指标

Our Abpromise guarantee covers the use of ab117166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab117166 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明Although stable 4°C for 4 weeks, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 10% Glycerol, 0.02% DTT, 0.32% Tris HCl

常规信息

  • 别名
    • MNDA
    • MNDA_HUMAN
    • Myeloid cell nuclear differentiation antigen
    • OTTHUMP00000024384
    • PYHIN3
    see all
  • 功能May act as a transcriptional activator/repressor in the myeloid lineage. Plays a role in the granulocyte/monocyte cell-specific response to interferon. Stimulates the DNA binding of the transcriptional repressor protein YY1.
  • 组织特异性Expressed constitutively in cells of the myeloid lineage. Found in promyelocyte stage cells as well as in all other stage cells including peripheral blood monocytes and granulocytes. Also appear in myeloblast cells in some cases of acute myeloid Leukemia.
  • 序列相似性Contains 1 DAPIN domain.
    Contains 1 HIN-200 domain.
  • 结构域Its N-terminal half (200 amino acids) is sufficient for maximum enhancement of YY1 DNA binding and a portion of this sequence is responsible for binding YY1.
  • 细胞定位Nucleus. Cytoplasm. Uniformly distributed throughout the interphase cell nucleus. Associates with chromatin.
  • Information by UniProt

Recombinant MNDA protein (ab117166)参考文献

ab117166 has not yet been referenced specifically in any publications.

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