Recombinant Leptin protein (ab9827)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli

技术指标

Our Abpromise guarantee covers the use of ab9827 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 内毒素水平< 0.100 Eu/µg
  • 形式Lyophilised
  • 补充说明Human Leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg leptin/gm of body weight for 7 days. Significant effects on body weight , food consumption, and plasma glucose levels were observed to saline-treated controls.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    n/a

  • 复溶Reconstitute in water to a concentration of 1.0-5.0 mg/ml.

常规信息

  • 别名
    • FLJ94114
    • LEP
    • LEP_HUMAN
    • LEPD
    • Leptin
    • Leptin (murine obesity homolog)
    • Leptin (obesity homolog, mouse)
    • Leptin Murine Obesity Homolog
    • Leptin Precursor Obesity Factor
    • OB
    • Obese protein
    • Obese, mouse, homolog of
    • Obesity
    • Obesity factor
    • Obesity homolog mouse
    • Obesity Murine Homolog Leptin
    • OBS
    • OTTHUMP00000212285
    see all
  • 功能May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
  • 疾病相关Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 序列相似性Belongs to the leptin family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant Leptin protein (ab9827)参考文献

ab9827 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. We recommend reconstituting in water to a concentration of 1.0-5.0 mg/ml. I have added this information to the datasheet for future reference. Please do not hesitate to contact me should you have any additional questi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"