Recombinant人WDR68 protein (denatured) (ab111624)

概述

  • 产品名称
    Recombinant人WDR68 protein (denatured)
    参阅全部 WDR68 蛋白酶
  • 蛋白长度
    Protein fragment
  • 描述
    Recombinant人WDR68 protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMVYAMNWSVRPDKRFRLALGSFVEEYNNKV QLVGLDEESSEFICRNTFDHPYPTTKLMWIPDTKGVYPDLLATSGDYLRV WRVGETETRLECLLNNNKNSDFCAPLTSFDWNEVDPYLLGTSSIDTTCTI WGLETGQVLGRVNLVSGHVKTQLIAHDKEVYDIAFSRAGGGRDMFASVGA DGSVRMFDLRHLEHSTIIYEDPQHHPLLRLCWNKQDPNYLATMAMDGMEV VILDVRVPCTPVARLNNHRACVNGIAWAPHSSCHICTAADDHQALIWD
    • 分子量
      34 kDa
    • 氨基酸
      19 to 295
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab111624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    ab111624 was denatured using detergent during conventional chromatography purification process.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 2.4% Urea

常规信息

  • 别名
    • AN11
    • Dcaf7
    • DCAF7_HUMAN
    • DDB1- and CUL4-associated factor 7
    • HAN11
    • Human anthocyanin
    • Petunia
    • Seven WD repeat protein of the AN11 family 1
    • SWAN 1
    • WD repeat domain 68
    • WD repeat protein An11 homolog
    • WD repeat-containing protein 68
    • WD repeat-containing protein An11 homolog
    • WDR68
    see all
  • 功能
    Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Belongs to the WD repeat DCAF7 family.
    Contains 4 WD repeats.
  • 细胞定位
    Cytoplasm. Nucleus. Overexpression of DIAHP1 or active RHOA causes translocation from the nucleus to cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE showing ab111624 at approximately 33.6kDa (3µg).

文献

ab111624 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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