Recombinant人Visfatin protein (ab109137)

概述

描述

  • 性质Recombinant
  • 来源HEK 293 cells
  • 氨基酸序列
    • AccessionP43490
    • 种属Human
    • 分子量52 kDa including tags
    • 氨基酸1 to 491
    • 标签DDDDK tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.
  • 应用

    Functional Studies

    SDS-PAGE

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • 补充说明 Shows adipogenic effects in stimulated differentiating 3T3-L1 cells.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: PBS

  • 复溶Reconstitute in distilled water

常规信息

  • 别名
    • 1110035O14Rik
    • AI314458
    • AI480535
    • DKFZP666B131
    • EC 2.4.2.12
    • MGC117256
    • NAmPRTase
    • Nampt
    • NAMPT_HUMAN
    • Nicotinamide phosphoribosyltransferase
    • PBEF
    • PBEF 1
    • PBEF1
    • Pre B cell colony enhancing factor
    • Pre B cell colony enhancing factor 1
    • Pre B cell enhancing factor
    • Pre-B cell-enhancing factor
    • Pre-B-cell colony-enhancing factor 1
    • VF
    • Visfatin
    see all
  • 功能Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway.
  • 组织特异性Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
  • 通路Cofactor biosynthesis; NAD(+) biosynthesis; nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1.
  • 序列相似性Belongs to the NAPRTase family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Visfatin protein 图像

  • Dimer formation of recombinant PBEF (ab109137).
    Purified ab109137 was separated by SDS-PAGE and Western blot analysis was performed using rabbit anti-Nampt polyclonal antibody. In the absence of DTT ab109137 formed a homodimer, a homomultimer.

Recombinant Human Visfatin protein (ab109137)参考文献

ab109137 has not yet been referenced specifically in any publications.

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