Recombinant人VEGFB protein (ab116402)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP49765
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MPVSQPDAPG HQRKVVSWID VYTRATCQPR EVVVPLTVEL MGTVAKQLVP SCVTVQRCGG CCPDDGLECV PTGQHQVRMQ ILMIRYPSSQ LGEMSLEEHS QCECRPKKKD SAVKPDRAAT PHHRPQPRSV PGWDSAPGAP SPADITHPTP APGPSAHAAP STTSALTPGP AAAAADAAAS SVAKGGA.
    • 分子量22 kDa including tags
    • 氨基酸22 to 207
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab116402 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml corresponding to a specific activity of less than 1,000,000 units/mg.
  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 90 % SDS-PAGE.
    ab116402 was purified by proprietary chromatographic techniques and filter sterilized.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 10% Glycerol, 0.32% Tris HCl

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • Vascular endothelial growth factor B
    • VEGF B
    • VEGF related factor
    • VEGF-B
    • VEGF-related factor
    • Vegfb
    • VEGFB_HUMAN
    • VEGFL
    • VRF
    see all
  • 功能Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
  • 组织特异性Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
  • 序列相似性Belongs to the PDGF/VEGF growth factor family.
  • 翻译后修饰VEGF-B186 is O-glycosylated.
  • 细胞定位Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
  • Information by UniProt

Recombinant human VEGFB protein (ab116402)参考文献

ab116402 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"