Full length protein
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Measured in a cell proliferation assay using NIH-3T3 mouse embryonic fibroblast. The ED50 for this effect is < 1ng/ml corresponding to a specific activity of less than 1,000,000 units/mg.
ab116402 was purified by proprietary chromatographic techniques and filter sterilized.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Constituents: 10% Glycerol, 0.32% Tris HCl
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- Vascular endothelial growth factor B
- Vascular endothelial growth factor-related factor
- VEGF B
Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
Belongs to the PDGF/VEGF growth factor family.
VEGF-B186 is O-glycosylated.
Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"