Recombinant人VEGF Receptor 2 protein (ab106310)



  • 性质Recombinant
  • 来源Insect cells
  • 氨基酸序列
    • AccessionP35968
    • 种属Human
    • 序列The soluble receptor protein consists of the first 6 extracellular domains and contains the unique C-terminal end of native Human soluble VEGF Receptor 2 (CGRETILDHSAEAVGMP) [Albuquerque et al.,Nature Medicine,2009] generated by alternative splicing.
    • 分子量105 kDa


Our Abpromise guarantee covers the use of ab106310 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Measured by its ability to bind to immobilized recombinant Human VEGF165 in a functional ELISA.
  • 应用

    Functional Studies


  • 纯度> 95 % SDS-PAGE.

  • 形式Lyophilised
  • 补充说明Endotoxin level: < 0.1 ng per ug. Measured by its ability to bind to immobilized recombinant Human VEGF165 in a functional ELISA.
  • Concentration information loading...


  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 25mM MES, 150mM Sodium chloride, pH 5.5

  • 复溶The lyophilized powder should be reconstituted in water or PBS to a concentration not lower than 100 µg/ml.


  • 别名
    • CD309
    • CD309 antigen
    • EC
    • Fetal liver kinase 1
    • FLK-1
    • FLK1
    • FLK1, mouse, homolog of
    • Kdr
    • Kinase insert domain receptor
    • Kinase insert domain receptor (a type III receptor tyrosine kinase)
    • KRD1
    • Ly73
    • Protein tyrosine kinase receptor FLK1
    • Protein-tyrosine kinase receptor flk-1
    • soluble VEGFR2
    • Tyrosine kinase growth factor receptor
    • Vascular endothelial growth factor receptor 2
    • VEGFR
    • VEGFR 2
    • VEGFR-2
    • VEGFR2
    see all
  • 功能Receptor for VEGF or VEGFC. Has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
  • 疾病相关Defects in KDR are associated with susceptibility to hemangioma capillary infantile (HCI) [MIM:602089]. HCI are benign, highly proliferative lesions involving aberrant localized growth of capillary endothelium. They are the most common tumor of infancy, occurring in up to 10% of all births. Hemangiomas tend to appear shortly after birth and show rapid neonatal growth for up to 12 months characterized by endothelial hypercellularity and increased numbers of mast cells. This phase is followed by slow involution at a rate of about 10% per year and replacement by fibrofatty stroma.
  • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylated. Dephosphorylated by PTPRB. Dephosphorylated by PTPRJ at Tyr-951, Tyr-996, Tyr-1054, Tyr-1059, Tyr-1175 and Tyr-1214.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human VEGF Receptor 2 protein 图像

  • SDS-PAGE showing ab106310

Recombinant Human VEGF Receptor 2 protein (ab106310)参考文献

ab106310 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry regarding ab106041 and for taking the time to provide some useful details of the experiments. I am very sorry to hear that you are having problems with this antibody.

After reading through the detailed protocol you k...

Read More

Thank you for contacting us.

The antibodies are viable for 10 years when stored at -20C, for 1 year when stored at 4C.

Please note that we recommend storing the antibodies at 4C for 1-2 weeks only. Some antibodies are prone to degrada...

Read More

Thank you for your patience while I looked into your question. I have heard back from the lab, and ab106310 is also only the extracellular domain of VEGF receptor 2, and is thus not suitable for kinase studies. However, ab42614 has been tested ...

Read More