The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
生物活性useful for Antibody Production and Protein Array
补充说明Best use within three months from the date of receipt of this protein.useful for Antibody Production and Protein Array
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.79% Tris HCl, 0.31% Glutathione Note: Glutathione is reduced
Cadherin 5 type 2
Cadherin 5, type 2 (vascular endothelium)
Cadherin 5, type 2, VE cadherin (vascular epithelium)
cadherin, vascular endothelial
cadherin, vascular endothelial, 1
Endothelial specific cadherin
Vascular endothelial cadherin
Vascular epithelium cadherin
功能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.
组织特异性Endothelial tissues and brain.
序列相似性Contains 5 cadherin domains.
翻译后修饰Phosphorylated on tyrosine residues by KDR/VEGFR-2. Dephosphorylated by PTPRB.
细胞定位Cell junction. Cell membrane. Found at cell-cell boundaries and probably at cell-matrix boundaries.