Recombinant人VAPB protein (ab101214)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO95292
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMAKVEQVLSL EPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGI IDAGASINVSVMLQPFDYDPNEKSKHKFMVQSMFAPTDTSDMEAVWKEAK PEDLMDSKLRCVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSS LDDTEVKKVMEECKRLQGEVQRLREENKQFKEEDGLRMRKTVQSNSPISA LAPTGKEEGLST
    • 分子量27 kDa including tags
    • 氨基酸1 to 222
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101214 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab101214 was purified using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: 0% None
    Constituents: 10% Glycerol, 20mM Tris HCl, pH 8.0

常规信息

  • 别名
    • ALS 8
    • ALS8
    • D2Abb2e
    • UNQ484/PRO983
    • Vamp 33b
    • VAMP associated 33 kDa protein
    • VAMP associated protein B
    • VAMP associated protein B and C
    • VAMP associated protein B/C
    • VAMP associated protein C
    • VAMP B
    • VAMP B VAMP C
    • VAMP B/VAMP C
    • VAMP C
    • VAMP vesicle associated membrane protein associated protein B and C
    • Vamp33b
    • VAMPB
    • VAMPB/VAMPC
    • VAMPC
    • VAP 33b
    • VAP B
    • VAP B/VAP C
    • VAP C
    • VAP33b
    • VAPB/VAPC
    • VAPC
    • Vesicle associated membrane protein associated protein B and C
    • Vesicle associated membrane protein associated protein B/C
    see all
  • 相关性VAPB contains 1 MSP domain and it may play a role in vesicle trafficking. Defects in VAPB are a cause of proximal adult autosomal dominant spinal muscular atrophy [MIM:182980]; also called late onset spinal muscular atrophy Finkel type. Spinal muscular atrophies are neurodegenerative disorders characterized by degeneration of lower motor neurons, leading to progressive paralysis muscular atrophy. This form is a late adult onset form of the disease (after age 20 years). The patients show a benign course, most of them remaining ambulatory 10 to 40 years after clinical onset.
  • 细胞定位Cell membrane; Single-pass type IV membrane. Intracytoplasmic membrane; Single-pass type IV membrane protein. Note: Present in the plasma membrane and in intracellular vesicles.

Recombinant Human VAPB protein 图像

  • ab101214 at 3 µg analysed by 15% SDS PAGE.

Recombinant Human VAPB protein (ab101214)参考文献

ab101214 has not yet been referenced specifically in any publications.

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