- 来源Insect cells
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 95
ab92591 is purified from auto-catalytic digestion of recombinant human urokinase produced in insect cells.
The amino terminal fragment (ATF) contains the Kringle and Epidermal Growth Factor domains and is separated from LMW uPA by cleavage at the Lys135-Lys136 bond.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituents: 0.1M Sodium chloride, 0.1M HEPES, pH 7.4
- 功能Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
- 组织特异性Expressed in the prostate gland and prostate cancers.
- 序列相似性Belongs to the peptidase S1 family.
Contains 1 EGF-like domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain.
- 翻译后修饰Phosphorylation of Ser-158 and Ser-323 abolishes proadhesive ability but does not interfere with receptor binding.
Information by UniProt
Recombinant Human Urokinase protein 图像
Recombinant Human Urokinase protein (ab92591)参考文献
has not yet been referenced specifically in any publications.
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