Recombinant人Ube2L3 protein (ab48775)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MAASRRLMKE LEEIRKCGMK NFRNIQVDEA NLLTWQGLIV PDNPPYDKGA FRIEINFPAE YPFKPPKITF KTKIYHPNID EKGQVCLPVI SAENWKPATK TDQVIQSLIA LVNDPQPEHP LRADLAEEYS KDRKKFCKNA EEFTKKYGEK RPVD
    • 氨基酸
      1 to 154

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技术指标

Our Abpromise guarantee covers the use of ab48775 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.
    Ube2L3 was overexpressed in E.coli and purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, 150mM Sodium chloride, 1mM DTT, pH 7.5

常规信息

  • 别名
    • E2 F1
    • L UBC
    • L-UBC
    • UB2L3_HUMAN
    • UBCE7
    • UbcH7
    • UbcM4
    • Ube2l3
    • Ubiquitin carrier protein L3
    • Ubiquitin conjugating enzyme E2 L3
    • Ubiquitin protein ligase L3
    • Ubiquitin-conjugating enzyme E2 L3
    • Ubiquitin-conjugating enzyme E2-F1
    • Ubiquitin-protein ligase L3
    see all
  • 功能
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
  • 组织特异性
    Ubiquitous, with highest expression in testis.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Belongs to the ubiquitin-conjugating enzyme family.
  • 翻译后修饰
    Ubiquitinated. The alteration of UBE2L3 protein levels during the S-phase of the cell cycle is due to ubiquitin-dependent proteasomal degradation.
  • 细胞定位
    Nucleus. Cytoplasm.
  • Information by UniProt

图片

  • 14% SDS-PAGE gel loaded with ab48775
    recombinant human Ube2L3 protein
    predicted molecular weight 17.9KDa

文献

ab48775 has not yet been referenced specifically in any publications.

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