Recombinant人UBE2I / UBC9 protein (ab51167)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED KDWRPAITIK QILLGIQELL NEPNIQDPAQ AEAYTIYCQN RVEYEKRVRA QAKKFAPS

技术指标

Our Abpromise guarantee covers the use of ab51167 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, 150mM Sodium chloride, 1mM DTT, pH 7.5

常规信息

  • 别名
    • C358B7.1
    • p18
    • SUMO 1 protein ligase
    • SUMO conjugating enzyme UBC9
    • SUMO-conjugating enzyme UBC9
    • SUMO-protein ligase
    • SUMO1 protein ligase
    • UBC9
    • UBC9_HUMAN
    • UBCE9
    • Ube2i
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein 9
    • Ubiquitin carrier protein I
    • Ubiquitin conjugating enzyme 9
    • Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9)
    • Ubiquitin conjugating enzyme E2I (UBC9 homolog, yeast)
    • Ubiquitin conjugating enzyme UbcE2A
    • Ubiquitin like protein SUMO 1 conjugating enzyme
    • Ubiquitin protein ligase E2I
    • Ubiquitin-conjugating enzyme E2 I
    • Ubiquitin-protein ligase I
    see all
  • 功能Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation.
  • 组织特异性Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus.
  • 通路Protein modification; protein sumoylation.
  • 序列相似性Belongs to the ubiquitin-conjugating enzyme family.
  • 细胞定位Nucleus. Cytoplasm. Mainly nuclear. In spermatocytes, localizes in synaptonemal complexes. Recruited by BCL11A into the nuclear body.
  • Information by UniProt

Recombinant Human UBE2I / UBC9 protein 图像

  • ab51167 in 14% SDS-PAGE

Recombinant Human UBE2I / UBC9 protein (ab51167)参考文献

ab51167 has not yet been referenced specifically in any publications.

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