Recombinant人UBE2D2 protein (Chemical Free) (ab81575)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 标签
      GST tag N-Terminus

相关产品

技术指标

Our Abpromise guarantee covers the use of ab81575 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Conjugation

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Lyophilised
  • 补充说明

    UbcH5b has 89% and 88% sequence identity with UbcH5a and UbcH5c respectively.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM HEPES, 100mM Sodium chloride, pH 8.0

常规信息

  • 别名
    • E2(17)KB2
    • OTTHUMP00000223475
    • OTTHUMP00000223476
    • OTTHUMP00000223477
    • OTTHUMP00000223478
    • OTTHUMP00000224375
    • PUBC 1
    • PUBC1
    • UB2D2_HUMAN
    • UBC 4
    • UBC 4/5
    • UBC4
    • UBC4/5
    • UBC4/5 homolog yeast
    • UBCH 5B
    • UBCH5B
    • UBE2D2
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein D2
    • Ubiquitin conjugating enzyme E2 17 kDa 2
    • Ubiquitin conjugating enzyme E2 D2
    • Ubiquitin conjugating enzyme E2D 2
    • Ubiquitin conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
    • Ubiquitin conjugating enzyme E2D 2 (UBC4/5 homolog yeast)
    • Ubiquitin protein ligase D2
    • Ubiquitin-conjugating enzyme E2 D2
    • Ubiquitin-conjugating enzyme E2(17)KB 2
    • Ubiquitin-conjugating enzyme E2-17 kDa 2
    • Ubiquitin-protein ligase D2
    see all
  • 功能
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of MAVS in the mitochondria by DDX58/RIG-I in response to viral infection. Essential for viral activation of IRF3.
  • 通路
    Protein modification; protein ubiquitination.
  • 序列相似性
    Belongs to the ubiquitin-conjugating enzyme family.
  • Information by UniProt

文献

ab81575 has not yet been referenced specifically in any publications.

客户评价及客户问答

There are currently no Customer reviews or Questions for ab81575.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

注册