Recombinant人UBE2D1 protein (ab111457)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP51668
    • 种属Human
    • 分子量17 kDa
    • 氨基酸1 to 147
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab111457 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Useful for in vitro ubiquitinylation reactions. Typical enzyme concentration to support conjugation in vitro is 100 nM to 1 µM depending upon conditions.
  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • 补充说明Useful for in vitro ubiquitinylation reactions. Typical enzyme concentration to support conjugation in vitro is 100 nM to 1 µM depending upon conditions.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.32% Tris HCl, 0.01% DTT

常规信息

  • 别名
    • E2(17)KB1
    • SFT
    • Stimulator of Fe transport
    • UB2D1_HUMAN
    • UBC 4/5
    • UBC4/5
    • UBC4/5 homolog
    • UBC4/5, S. cerevisiae, homolog of
    • UBCH 5
    • UBCH 5A
    • UbcH5
    • UBCH5A
    • Ube2d1
    • Ubiquitin carrier protein
    • Ubiquitin carrier protein D1
    • Ubiquitin conjugating enzyme E2 17 kDa 1
    • Ubiquitin conjugating enzyme E2 D1
    • Ubiquitin conjugating enzyme E2D 1
    • Ubiquitin conjugating enzyme E2D 1 (UBC4/5 homolog yeast)
    • Ubiquitin conjugating enzyme UBCH5A
    • Ubiquitin protein ligase D1
    • Ubiquitin-conjugating enzyme E2 D1
    • Ubiquitin-conjugating enzyme E2(17)KB 1
    • Ubiquitin-conjugating enzyme E2-17 kDa 1
    • Ubiquitin-protein ligase D1
    see all
  • 功能Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
  • 组织特异性Ubiquitous. Up-regulated in livers of iron-overloaded patients with hereditary hemochromatosis.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the ubiquitin-conjugating enzyme family.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human UBE2D1 protein (ab111457)参考文献

ab111457 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111457.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"