重组人TWEAKR/FN14蛋白(ab201431)
Key features and details
- Expression system: Escherichia coli
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies, HPLC
描述
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产品名称
重组人TWEAKR/FN14蛋白
参阅全部 TWEAKR/FN14 蛋白酶 -
生物活性
Fully biologically active when compared to standard.
The ED50 as determined by inhibiting TWEAK-dependent proliferation of Human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of > 3.3 × 104 IU/mg, in the presence of 15 ng/ml of TWEAKR.
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纯度
> 95 % SDS-PAGE.
> 95 % by HPLC. -
表达系统
Escherichia coli -
Accession
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蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
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种属
Human -
序列
EQAPGTAPCSRGSSWSADLDKCMDCASCRARPHSDFCLGCAAAPPAPFRL LWP -
预测分子量
6 kDa -
氨基酸
28 to 80
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技术指标
Our Abpromise guarantee covers the use of ab201431 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
SDS-PAGE
Functional Studies
HPLC
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形式
Lyophilized -
补充说明
This product was previously labelled as TWEAKR
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Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS
0.2µm filteredThis product is an active protein and may elicit a biological response in vivo, handle with caution.
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复溶Briefly centrifuge prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
常规信息
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别名
- CD 266
- CD266
- CD266 antigen
see all -
功能
Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins. -
组织特异性
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas. -
序列相似性
Contains 1 TNFR-Cys repeat. -
细胞定位
Membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab201431 尚未被引用在任何文献中。