Recombinant人TWEAKR protein (ab117223)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9NP84
    • 种属Human
    • 分子量6 kDa

技术指标

Our Abpromise guarantee covers the use of ab117223 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性Determined by its ability to inhibit TWEAKR induced weak cell death of HT29 cells, with an expected ED50 of 1.0-3.0 µg/ml.
  • 应用

    SDS-PAGE

    Functional Studies

    HPLC

  • 内毒素水平< 1.000 Eu/µg
  • 纯度> 98 % SDS-PAGE.
    Purity is determined to be >98% by SDS PAGE and HPLC analysis
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

    Constituent: 99% PBS

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Reconstitute with 250µl distilled water.
    Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommended that the vial is gently mixed after reconstitution. Best use within three months from the date of reconstitution.

常规信息

  • 别名
    • CD 266
    • CD266
    • CD266 antigen
    • FGF inducible 14
    • FGF-inducible 14
    • Fibroblast growth factor inducible immediate early response protein 14
    • Fibroblast growth factor-inducible immediate-early response protein 14
    • FN 14
    • FN14
    • TNFRSF 12A
    • TNFRSF12A
    • TNR12_HUMAN
    • Tumor necrosis factor receptor superfamily member 12A
    • TWEAK R
    • Tweak receptor
    • Tweak-receptor
    • TweakR
    see all
  • 功能Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
  • 组织特异性Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
  • 序列相似性Contains 1 TNFR-Cys repeat.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant human TWEAKR protein (ab117223)参考文献

ab117223 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"