Recombinant人TTC11 protein (ab119156)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9Y3D6
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG
    • 分子量16 kDa including tags
    • 氨基酸1 to 122
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab119156 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 10% Glycerol

常规信息

  • 别名
    • 2010003O14Rik
    • CGI 135
    • CGI135
    • FIS 1
    • FIS1
    • Fis1 homolog
    • FIS1, S. cerevisiae, homolog of
    • FIS1_HUMAN
    • Fission 1 (mitochondrial outer membrane) homolog
    • Fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
    • Fission 1 (mitochondrial outer membrane) homolog (yeast)
    • Fission 1 homolog
    • H NH0132A01.6
    • hFis 1
    • hFis1
    • Mitochondrial fission 1 protein
    • Tetratricopeptide repeat domain 11
    • Tetratricopeptide repeat protein 11
    • TPR repeat protein 11
    • TTC 11
    see all
  • 功能Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
  • 序列相似性Belongs to the FIS1 family.
    Contains 1 TPR repeat.
  • 结构域The C-terminus is required for mitochondrial or peroxisomal localization, while the N-terminus is necessary for mitochondrial or peroxisomal fission, localization and regulation of the interaction with DNM1L.
  • 翻译后修饰Ubiquitinated by MARCH5.
  • 细胞定位Mitochondrion outer membrane. Peroxisome membrane.
  • Information by UniProt

Recombinant Human TTC11 protein (ab119156)参考文献

ab119156 has not yet been referenced specifically in any publications.

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