Recombinant人Tryptophanyl tRNA synthetase protein (ab116687)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP23381
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMPNSEPASLLELFNSIATQGELVRSLKAGN ASKDEIDSAVKMLVSLKMSYKAAAGEDYKADCPPGNPAPTSNHGPDATEA EEDFVDPWTVQTSSAKGIDYDKLIVRFGSSKIDKELINRIERATGQRPHH FLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFT KWLQDVFNVPLVIQMTDDEKYLWKDLTLDQAYSYAVENAKDIIACGFDIN KTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISF PAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVAPRIGYP KPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGG RDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYTSGAMLTGEL KKALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRKLSFDFQ
    • 分子量55 kDa including tags
    • 氨基酸1 to 471
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab116687 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 90 % SDS-PAGE.
    ab116687 is purified by proprietary chromatographic techniques.
  • 形式Liquid
  • 补充说明Although stable at 4°C for 1 week, ab116687 should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Please see notes section.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.02% DTT, 0.58% Sodium chloride, 10% Glycerol

常规信息

  • 别名
    • Gamma 2
    • GAMMA-2
    • Gamma2
    • hWRS
    • IFI 53
    • IFI53
    • IFP 53
    • IFP53
    • Interferon induced protein 53
    • Interferon-induced protein 53
    • SYWC_HUMAN
    • T2-TrpRS
    • TrpRS
    • Tryptophan tRNA ligase, cytoplasmic
    • Tryptophan tRNA ligase
    • Tryptophan tRNA ligase 1 cytoplasmic
    • Tryptophan--tRNA ligase
    • Tryptophanyl tRNA synthetase
    • Tryptophanyl tRNA synthetase cytoplasmic
    • WARS
    • WARS protein
    • WRS
    see all
  • 功能Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
  • 序列相似性Belongs to the class-I aminoacyl-tRNA synthetase family.
    Contains 1 WHEP-TRS domain.
  • 翻译后修饰Proteolytic cleavage generates 2 forms; T1-TrpRS and T2-TrpRS.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Tryptophanyl tRNA synthetase protein (ab116687)参考文献

ab116687 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116687.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"