Recombinant人TPM4 protein (ab105576)

概述

  • 产品名称
    Recombinant人TPM4 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI
    • 分子量
      31 kDa
    • 氨基酸
      1 to 248
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab105576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF-TOF
  • 纯度
    > 85 % SDS-PAGE.
    ab105576 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8

常规信息

  • 别名
    • epididymis secretory protein Li 108
    • HEL-S-108
    • TM30p1
    • TMP 4
    • TPM4
    • TPM4_HUMAN
    • Tropomyosin 4
    • Tropomyosin alpha 4 chain
    • Tropomyosin alpha-4 chain
    • Tropomyosin-4
    • wu:fb06e07
    • zgc:103436
    • zgc:63909
    see all
  • 功能
    Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 组织特异性
    Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
  • 序列相似性
    Belongs to the tropomyosin family.
  • 结构域
    The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
  • 细胞定位
    Cytoplasm > cytoskeleton.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of ab105576 (3ug)

文献

ab105576 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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