Recombinant人TPM4 protein (ab105576)

概述

  • 产品名称Recombinant人TPM4 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP67936
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH MAGLNSLEAV KRKIQALQQQ ADEAEDRAQG LQRELDGERE RREKAEGDVA ALNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRAMK DEEKMEIQEM QLKEAKHIAE EADRKYEEVA RKLVILEGEL ERAEERAEVS ELKCGDLEEE LKNVTNNLKS LEAASEKYSE KEDKYEEEIK LLSDKLKEAE TRAEFAERTV AKLEKTIDDL EEKLAQAKEE NVGLHQTLDQ TLNELNCI
    • 分子量31 kDa
    • 氨基酸1 to 248
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab105576 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF-TOF
  • 纯度> 85 % SDS-PAGE.
    ab105576 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 2mM DTT, 100mM Sodium chloride, pH 8

常规信息

  • 别名
    • epididymis secretory protein Li 108
    • HEL-S-108
    • TM30p1
    • TMP 4
    • TPM4
    • TPM4_HUMAN
    • Tropomyosin 4
    • Tropomyosin alpha 4 chain
    • Tropomyosin alpha-4 chain
    • Tropomyosin-4
    • wu:fb06e07
    • zgc:103436
    • zgc:63909
    see all
  • 功能Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
  • 组织特异性Detected in cardiac tissue and platelets, the form found in cardiac tissue is a higher molecular weight than the form found in platelets. Expressed at higher levels in the platelets of hypertensive patients with cardiac hypertrophy than in the platelets of hypertensive patients without cardiac hypertrophy (at protein level).
  • 序列相似性Belongs to the tropomyosin family.
  • 结构域The molecule is in a coiled coil structure that is formed by 2 polypeptide chains. The sequence exhibits a prominent seven-residues periodicity.
  • 细胞定位Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human TPM4 protein 图像

  • 15% SDS-PAGE analysis of ab105576 (3ug)

Recombinant Human TPM4 protein (ab105576)参考文献

ab105576 has not yet been referenced specifically in any publications.

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