The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
% SDS-PAGE. ab123199 is purified using conventional chromatography techniques.
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00 Constituents: 0.02% DTT, 0.32% Tris HCl, 20% Glycerol
Putative MAPK activating protein PM14
Putative MAPK-activating protein PM14
Putative NF kappa B activating protein 20
Putative NF-kappa-B-activating protein 20
TRAF interacting protein with FHA domain containing protein A
TRAF-interacting protein with FHA domain-containing protein A
TRAF2 binding protein
功能Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.